Eleven of these 13 genes (NID2, ACTN1, CCL5, FGL1, KIF14, TIAM1, NDNF, CCN1, TGFB2, SNAI2, CCDC80) were down- and two (SIGLEC1, ABI3BP) upregulated at the cyst stage (Fig. 10C). The gene discussed is ACTN1; the disease is cyst.