KMT2D and cancer: The pathological mutations identified in a set of HNSCC and potentially premalignant (oral) lesion-derived cell lines and primary cells derived from potentially premalignant (oral) lesions predominantly involved a relatively small set of genes reported previously (TP53, KMT2D, CDKN2A, PIK3CA, NOTCH1, and FAT1) but also other predicted cancer drivers (MGA, PABPC3, NR4A2, NCOR1, and MACF1).