CD8A and neoplasm: Notably, the fraction of detected aberrant inflammatory CD8 + T cells positively correlated with the number of MUM1 + plasma cells, suggesting a tumor-load dependent accumulation of aberrant inflammatory CD8 + T cells in the bone marrow at ID, with LAT1 and CXCR3 serving as accurate biomarkers (Fig. 5f and Supplementary Fig. 6c).