Importantly, the mean expression intensities of CXCR3, as well as LAT1 in CD8 + T cells were highly elevated in MM patients compared to B cell Non-Hodgkin lymphoma and MDS control cohorts, confirming the specific enrichment of aberrant inflammatory CD8 + T cells in MM (Fig. 5f and Supplementary Fig. 6c). Here, CD8A is linked to myelodysplastic syndrome.