To further assess the value of surface CXCR3 expression as a marker for myeloma-associated CD8 + T cells, we subjected BM CXCR3 + and CXCR3- CD8 + T cells from an independent cohort of 7 MM patients to bulk RNA-sequencing (Supplementary Fig. 6b). This evidence concerns the gene CXCR3 and Miyoshi myopathy.