At the 21-week timepoint, most of the KANK1-WTPyMT tumors reached the volume and weight approved by the ethical committee, whereas the KANK1-KOPyMT tumor weights were comparable to those of the KANK1-WTPyMT tumors measured at the 16-week time point (Fig. 2b). This evidence concerns the gene KANK1 and neoplasm.