This finding was further supported by the positive correlation between the subcellular localization of KANK1 at plasma membrane and TAZ in the nucleus56 (Fig. 10b), Third, inspection of the TCGA revealed a positive correlation between KANK1 mRNA levels and mRNA levels of the TAZ targets, CTGF and CYR61 in luminal breast cancers (Supplementary Fig. 15b–g). Here, CCN2 is linked to breast carcinoma.