INS and polycystic ovary syndrome: The mean changes for serum glucose concentration at 30 (−35.24; 95% CI: −62.69, −7.79; P = 0.012), 40 (−44.85; 95% CI: −74.93, −14.78; P = 0.003) and 60 (−39.84; 95% CI: −66.14, −13.55; P = 0.003) min after insulin injection during IPITT in the rat model of PCOS were significantly lower than their control with increasing age, possibly representing IR in the rat model of PCOS with increasing age.