Because E2F1 and E2F7 appeared to have opposite effects on prognosis (Fig. 1, G and I) and MYBL2 is a potential E2F target gene in GC cells, we next established correlations between the ratio of E2F1 and E2F7 mRNA levels and the prognosis of patients with GC. The gene discussed is E2F7; the disease is gastric cancer.