In the MR analysis pertaining to immune cell characteristics and colorectal cancer, we observed that the count of SNPs integrated into CD25 on CD39+ activated CD4 regulatory T cells (ebi-a-GCST90001940), and CD25 on CD39+ CD4 regulatory T cells (ebi-a-GCST90001935), was <3. Here, ENTPD1 is linked to colorectal cancer.