However, research has proposed that KCNQ1OT1, a LncRNA associated with KCNQ1, plays a crucial role in IDD.[44] Our findings revealed that KCNQ1 potentially contributes to the development of IDD via the Notch signaling pathway, as indicated by GSEA. Here, KCNQ1OT1 is linked to intervertebral disk degenerative disorder.