Specifically, the type of anemia (predominantly normocytic) is associated with higher Glasgow Prognostic Score (mGPS), elevated C-reactive protein (CRP), and interleukin-8 (IL-8) levels, underscoring a significant link between anemia and systemic inflammation.[5,15] Chronic inflammation is a critical risk factor for CRC. This evidence concerns the gene CXCL8 and colorectal carcinoma.