NEFL and Cognitive impairment: Similarly, another study comparing Black and nHW older adults with mild cognitive impairment found that plasma levels of Aβ42, Aβ40, p-tau181, and neurofilament light (NfL) were consistently lower in African American individuals after adjusting for demographic characteristics, educational attainment, cognition, APOE ε4 genotype, and cardiovascular factors [12].