INS and diabetic cardiomyopathy: The KEGG enrichment analysis revealed that these differential metabolites were mainly involved in carbohydrate digestion and absorption, glycerophospholipid metabolism, galactose metabolism, taste transduction, retrograde endocannabinoid signaling, insulin resistance, advanced glycation end-product (AGE) receptor for advanced glycation end-product (RAGE) signaling pathway in diabetic complications, cholesterol metabolism, diabetic cardiomyopathy, etc. (Fig. S2)