Although upregulation of select genes pivotal for fatty acid oxidation (such as Cpt, Acox, Ehhadh, and Acaa), potentially linked to PPARα activity, was also observed in BBR‐treated hepatocytes, the diminished levels of FFAs and FFA‐CoAs indicate that this upregulation may not be sufficient to mitigate BBR‐induced hepatic steatosis, as depicted in Figure 3G. The gene discussed is ACAA1; the disease is Hepatic steatosis.