Even though following infection, the cells had increased surface expression of Lamp2 (Figure S2G), as did the released lEVs (Figure S2H) implying a better capability of acting as decoys by competing for Mtr (gp82) / HeLa cell (Lamp2) interactions, set against this there is the many‐fold size differential between lEVs (200–500 nm) and Mtr (16–42 μm). The gene discussed is MTR; the disease is infection.