TRPC4 and mood disorder: In addition, TRPC4-containing channel may also be involved in other processes regulated by CBD in the CNS, such as epilepsy (von Wrede et al., 2021; Zanelati et al., 2010), social stress (Brancato et al., 2023), and mood disorders (Linge et al., 2016; Zanelati et al., 2010).