Among the most relevant mechanisms responsible of the multidrug resistance (MDR) development in clinical setting, is the overexpression of extrusion pumps including multidrug resistance gene 1 (MDR1) and corresponding P-glycoprotein protein (P-gp) that severely limits the success of chemotherapy in ovarian cancer treatment (Guppy et al., 2005), statistically shortening the overall survival of ovarian cancer patients (Kamazawa et al., 2002). The gene discussed is ABCB1; the disease is ovarian carcinoma.