PGP and ovarian carcinoma: Among the most relevant mechanisms responsible of the multidrug resistance (MDR) development in clinical setting, is the overexpression of extrusion pumps including multidrug resistance gene 1 (MDR1) and corresponding P-glycoprotein protein (P-gp) that severely limits the success of chemotherapy in ovarian cancer treatment (Guppy et al., 2005), statistically shortening the overall survival of ovarian cancer patients (Kamazawa et al., 2002).