One volunteer in the high-dose group 4, previously discussed as having a larger number of AEs after aerosol BCG-challenge, was found to have a transient raise in bilirubin (grade 2) and alanine transaminase (grade 1) on D2 of the study; this was accompanied by a raised white cell count (grade 1) and grade 1 hyponatraemia. The gene discussed is GPT; the disease is Hyponatremia.