We have noticed that the septic shock patients had a higher rate of infection by Gram-positive bacteria and fungus than the sepsis patients (45.3% vs. 24.7%, P < 0.05), and we tried to compare the concentration of parameters (including MT-ND6 and ANXA1) in patients with different bacterial culture results, but no statistically significant difference was observed in the both cohort (Data not shown). The gene discussed is ANXA1; the disease is Sepsis.