Compared with the lowest RC group, participants in the increased RC group were significantly more likely to have diabetes, hypertension, hyperlipidemia, CVD, CKD, elevated BMI, WC, WBC, Neu, Lym, PLT, Hb, ALT, ALP, GGT, Scr, UA, TC, TG, LDL-C, FPG, HbA1c, iron and decreased FIPR and HDL-C levels (all P<0.05). The gene discussed is GPT; the disease is chronic kidney disease.