A recent study demonstrated that exosomes containing lncRNA SNHG3 released by CAFs blocked mitochondrial oxidative phosphorylation (OXPHOS) and boosted glycolysis; exosomes were taken up by breast cancer cells, and the delivered SNHG3 increased PKM expression by sponging miR‐330‐5p.127. The gene discussed is SNHG3; the disease is breast cancer.