The risk prediction model included 8 predictors as follows(named ADOCHBIU): duration of diabetes (OR=2.276, 95%CI 2.097 ̃2.469), urinary microalbumin(OR=0.864, 95%CI 0.798 ̃0.935), oral hypoglycemic agents (OR=1.345, 95%CI 1.243 ̃1.452), cognitive impairment (OR=1.226, 95%CI 1.178 ̃1.276), insulin usage (OR=1.002, 95%CI 0.948 ̃1.060), hypertension (OR=1.113, 95%CI 1.103 ̃1.124), blood glucose monitoring (OR=1.909, 95%CI 1.791 ̃2.036), and abdominal circumference (OR=2.998, 95%CI 2.972 ̃3.024). This evidence concerns the gene INS and hypertensive disorder.