AML: acute myeloid leukemia; AZA: azacitidine; VEN: venetoclax; FLT3: FMS-like tyrosine kinase 3; ALL: acute lymphoblastic leukemia; CAR: chimeric antigen receptor; MDS: myelodysplastic syndromes; CPX-351: a liposomal formulation of daunorubicin and cytarabine; DAC: decitabine; B-ALL: B-lineage acute lymphoblastic leukemia. The gene discussed is FLT3; the disease is myelodysplastic syndrome.