The semiquantitative densitometric scanning of protein dot intensity on the dot-blots revealed that similar to ThT fluorescence levels, the intensity of tau aggregates captured by FTA on the blots was significantly higher in tauopathies than in normal controls by both RD4 (Fig. 6E) and RD3 antibodies (Fig. 6F). The gene discussed is RD3; the disease is tauopathy.