According to the Pe ́rez-Guisado et al. [52] study, a 12-week Spanish Ketogenic Mediterranean Diet (SKMD) (< 30 g carbohydrate/day) significantly improved ALT (P < 0.001) and AST (P < 0.001) levels in 14 obese men with NAFLD. This evidence concerns the gene GPT and metabolic dysfunction-associated steatotic liver disease.