Our result show that Linex treatment has the most significant immunmodulatory effect in shifting immune response toward Th1 where IL-4 and IL-13 show significant decrease to 33.16 pg/mL and 41.92 pg/mL respectively compared to infection control group 56.10 pg/mL and 60.74 pg/mL respectively, and so addition of Linex to Albendazole enhance the immune response against muscular phase of Trichinella than Albendazole effect alone. This evidence concerns the gene IL13 and infection.