VEGF/NRP-1 phosphorylate NF-κB-p65 and β-catenin, which in turn leads to the VEGF/NRP-1/NF-κB-p65 or VEGF/NRP-1/β-catenin signaling cascades, accelerating BC cell motility, invasion, metastasis, and EMT initiation [80]. This evidence concerns the gene NRP1 and breast cancer.