Not surprisingly, an overwhelming number of the top 25 upregulated DEGs are known to promote cancer metastasis and invasion (Crip1, Gfap, Sparcl1, Tmsb4x, Apoe, Ier2, Sparc, Cpe, Fabp5, Cdk2ap1, Jpt1, Vim, Ckb)52–64, NSC/GSC maintenance (Id1, Id3, Hes5, Gfap, Lgals1, Sparcl1, Tmsb4x, Fos)54,65–71, and/or resistance to chemotherapy (Crip1, Gfap, Apoe, Mt1, Mt3, Lgals1)64,69,72–74 (Fig. 9f). Here, ID1 is linked to cancer.