ZFR and glioma: Previously, the RNA-binding zinc-finger protein-encoding gene, Zfp36l1, was also shown to control oligodendrocyte-astrocyte fate transition, whereby conditional knock-out results in downregulation of oligodendrocyte lineage genes in favor of upregulation of astrocyte-lineage genes in both the developing forebrain and tumors of a glioma mouse model93.