FBP1 and breast carcinoma: Differences in FBP1 expression also exist in different types of breast cancer; for example, basal-like breast cancer cells have a lower level of FBP1 expression than luminal breast cancer cells do, and FBP1 deficiency induces glycolysis and leads to an increase in glucose uptake, which is critical for EMT and basal-like breast cancer [114, 115].