ITGB3 and cancer: Using the The Cancer Genome Atlas (TCGA) Pan Cancer Atlas—Breast Invasive Carcinoma dataset (49) (n = 105), we found a moderate, positive correlation between IGF-1R and ITGB1 protein expression (Spearman = 0.49, p = 1.35 × 10−7), and a weak, positive correlation between IGF-1R and ITGB3 protein expression (Spearman = 0.33, p = 1.271 × 10−3) (Fig. 2A).