NFKB1 and neoplasm: The translocation of the bacterial components called Pathogen-Associated Molecular Patterns (PAMPs), triggers inflammatory responses through the Toll-Like Receptor (TLR), followed by the activation of NF-kB, whose overexpression induced by lymphocyte lymphotoxins, by the NF-kB, TNF-α and IFNs signaling genes, acts as a promoter of hepatocarcinogenesis, being a crucial determinant in tumor recurrence.