Our results confirm the separate mechanism of regulation of this cadherin achieved by inhibition of CHI3L1 in our studies, suggesting that highest concentration of G721-0282 leads to a reduction of N-cadherin expression in our spheroid model of GBM at the protein level in immunoblotting and immunohistochemical reaction as well as at the mRNA level. Here, CDH17 is linked to glioblastoma.