During the process of backward stepwise selection, age, sex, BMI, diabetes mellitus, heart disease, peripheral vascular disease, ARBs, preoperative hemoglobin concentration, preoperative albumin concentration, dopamine, anesthetic agent, MIE, reconstruction route, total intravenous fluid volume, hydroxyethyl starch, and estimated blood loss were eliminated from the multivariable regression analysis model (Table 3). The gene discussed is ALB; the disease is diabetes mellitus.