Mice heterozygous for both Scn2a and Kcn1, a gene encoding for the pore-forming subunit of the voltage-gated potassium channel KV1.1(Scn2a+/−;Kcna1+/−), have reduced anxiety and autism-like behaviors compared to Scn2a+/− mice (Indumathy et al., 2021). Here, SCN2A is linked to autism.