However, there was no significant difference in TP53, TNF, TLR4, TGFB1, PTGS2, PTEN, PPARG, MTOR, MMP9, INS, IL6, IL1B, IL10, IFNG, ESR1, CASP3, ALB, AKT1, GSK3A, ERBB2, IL1A, ICAM1, CAV1, and APP levels between control and AD groups in the hippocampus (data not shown). The gene discussed is PTGS2; the disease is Alzheimer disease.