However, there was no significant difference in TP53, TNF, TLR4, TGFB1, PTGS2, PTEN, PPARG, MTOR, MMP9, INS, IL6, IL1B, IL10, IFNG, ESR1, CASP3, ALB, AKT1, GSK3A, ERBB2, IL1A, ICAM1, CAV1, and APP levels between control and AD groups in the hippocampus (data not shown). This evidence concerns the gene ESR1 and Alzheimer disease.