TLR4 and Alzheimer disease: However, there was no significant difference in TP53, TNF, TLR4, TGFB1, PTGS2, PTEN, PPARG, MTOR, MMP9, INS, IL6, IL1B, IL10, IFNG, ESR1, CASP3, ALB, AKT1, GSK3A, ERBB2, IL1A, ICAM1, CAV1, and APP levels between control and AD groups in the hippocampus (data not shown).