All these practices (consisting of avoidance of nephrotoxic agents, discontinuation of angiotensin-converting enzyme inhibitors and angiotensin receptor blockers for the first 48 h after surgery, close monitoring of serum creatinine and urine output, avoidance of hyperglycemia for the first 72 h after surgery, consideration of alternatives to radiocontrast agents, and close hemodynamic monitoring using a prespecified algorithm) should be part of routine clinical practice in all ICUs that treat patients with this high level of complexity. The gene discussed is ACE; the disease is Hyperglycemia.