BP, blood pressure; CHO cholesterol; HDL, high-density lipoprotein; LDL, low-density lipoprotein; BMI, body mass index; HbA1c, glycated hemoglobin; DM, diabetes mellitus; CKD, chronic kidney disease; NT-proBNP, N-terminal pro-B-type natriuretic peptide. This evidence concerns the gene NPPB and chronic kidney disease.