SMOX and infection: Using an acute infection model with wild-type (WT) C57BL/6 mice (Fig. 2A), we previously found that PAO1 ΔmexEFoprN was hypervirulent relative to PAO1 WT, causing 90% mortality of mice at 48 h post-infection compared to 50% mortality of PAO1 WT infected mice at 96 h21.