A significant finding of this study is the remarkable ability of BBR to potently and correlatively decrease viability of TZM-bl cervical cancer cells, inhibit expression of CA-HIV RNA (Tat-Rev, Gag-Pol) species, block Tat mediated HIV LTR promoter transactivation, and inhibit HIV Tat-mediated migration and matrix invasion of HIV infected TZM-bl cells. This evidence concerns the gene TAT and cervical cancer.