PSTPIP1 and acne: PSTPIP1 mutations have been detected in autoinflammatory syndromes associated with HS, namely, PASH (pyoderma gangrenosum, acne, and hidradenitis suppurativa) syndrome and PAPASH (pyogenic arthritis, pyoderma gangrenosum, acne, and Hidradenitis suppurativa) syndrome (Nikolakis et al., 2021).