In the upregulated group, significantly enriched pathways included systemic lupus erythematosus, arginine biosynthesis, Vibrio cholerae infection, nitrogen metabolism, rheumatoid arthritis, intestinal IgA production immune network, collecting duct acid secretion, Staphylococcus aureus infection, and asthma, among others (Figure 1D). The gene discussed is CD79A; the disease is staphylococcus aureus infection.