Cellular uptake, cytotoxicity, dead cell, ROS, ɣ H2AX, p53, DNA damage, apoptosis, cell deaths↑; mitochondrial membrane potential, invasion, migration, colony formation↓; tumor size↓; accumulation of dead cells and fluids, neutrophil infiltration, fibroblastic activity↑; spleen enlargement, mild to moderate hypertrophy of lymphatic follicles with hyperplasia of lymphocytes. The gene discussed is TP53; the disease is neoplasm.