The anticancer potential of curcumin is observed in multiple cancer types, such as breast cancer and OSCC, and is associated with the suppression of the activity of Tregs and TAMs, as well as the downregulation of TGF-β and IL-10 by the MAO-A/STAT6 signaling pathway (Bhattacharyya et al., 2010; Jiang, 2023). The gene discussed is TGFB1; the disease is cancer.