Our findings indicate a significant correlation between ITGAL expression and various factors including cell motility, B cell activation, T cell activation, lymphocyte-mediated immunity, leukocyte-mediated immunity, leukocyte proliferation, cellular community, transport and catabolism, as well as carbohydrate metabolism in HNSCC (Figures 8A, B). This evidence concerns the gene ITGAL and head and neck squamous cell carcinoma.