MAP3K13 and head and neck squamous cell carcinoma: Knocking down LZK with siRNA or shRNA significantly reduced cell viability and proliferation in 3q amplicon-positive HNSCC cells (CAL33, BICR56, Detroit562, and BICR6), but not control immortalized diploid cells (oral keratinocytes, OKF6, or bronchial epithelial cells, BEAS-2B) or HNSCC cells lacking amplified LZK (MSK921 and BICR22) (1).