MAP3K13 and head and neck squamous cell carcinoma: We identified 5 patient-derived xenograft mouse models (PDX 391396-364-R, 295223-140-R, 899872-116-R, 226611-082-R, and 653398-132-R) with amplified MAP3K13 (at least 4 copies) and 31 PDXs with gains of MAPK3K13 (3 copies) in 58 HNSCC PDX models from the NCI Patient-Derived Models Repository (PDMR) (Figure 4A, B) (23–25).