This gene, along with neighboring genes such as KANSL1 in chromosomal band 17q21.31, has attracted interest for potential associations with diseases including Progressive Supranuclear Palsy (PSP), Frontotemporal Dementia (FTD), Dementia with Lewy Bodies (DLB), and Alzheimer’s disease (AD)10, 11, 12. Here, KANSL1 is linked to Alzheimer disease.