For example, only scPrediXcan identifies two genes on chromosome 16 that have been implicated in SLE pathogenesis: PYCARD (also named ASC) in CD4+ alpha-beta T cell (p=7.8 × 10−48) and ITGAM in CD14+ monocytes (p=4.3 × 10−41)34,35. The gene discussed is PYCARD; the disease is systemic lupus erythematosus.