In the CT2A mouse model, Choi et al. have instead shown that tumor debulking resulted in a reduction of MDSC along with the recruitment of effector T lymphocytes (CD4/CD8 T cells) into the resection area at 2, 4 and 6 days post-surgery and increased dendritic cells at day 4 post-surgery compared to unresected GBM-tumors bearing animals [17]. This evidence concerns the gene CD4 and glioblastoma.