In this study, the level of hs-cTnT in patients with severe renal insufficiency was significantly higher than that in patients with mild renal insufficiency, and the level of hs-cTnT was positively correlated with the deterioration of renal function (0.655, P < 0.001), suggesting a certain relationship between the level of hs-cTnT and the severity of kidney injury. The gene discussed is TNNT2; the disease is Renal insufficiency.