The correlation heat map analysis indicated significant positive correlations between TACC3 and immune-related genes such as CD276, CD70, IDO1, LAG3, PDCD1, TIGIT, and TNRSF9 in both the NSCLC and LUAD datasets (P < 0.05; Fig. 6A and B). The gene discussed is LAG3; the disease is non-small cell lung carcinoma.