Five synaptic genes were selected based on their prognosis status in gliomas (higher expression = better prognosis): SNAP25 (encoding Synapsis Associated Protein 25), CPLX1 (encoding Complexin 1), SYN1, DLG4 (encoding Postsynaptic Density Protein 95), and GABRG2 (encoding Gamma-Aminobutyric Acid Type A Receptor Subunit Gamma2). The gene discussed is SYN1; the disease is central nervous system cancer.