Patients with heart failure (HF) showed significantly increased plasma/serum levels of osteoglycin [97], glypican‐4 [98], endocan [99], syndecan‐1 [100, 101], syndecan‐4 [102, 103, 104], endostatin [44], and perlecan [105], compared with control subjects. This evidence concerns the gene OGN and hydrops fetalis.